11 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... extramedullary disease ... manifestations, hypoxia, CXR ... lymphoid organs When Cancer ... #Leukemia #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... common • Imaging: CXR ... - pulmonary opacities ... diagnosis #management #hematology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Large volume feeding ... Blood cultures • CXR ... ) • CXR upright ... foreign body, cancer ... Lung #Abscess #pulmonary
Differential diagnosis
The table summarizes the most common diseases, that present with consolidation.
Chronic diseases are indicated in
diagnosis The table ... - Cells - tumor ... respond to the treatment ... #Diagnosis #Radiology ... #Pulmonary #CXR
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Lymphoma • Lung cancer ... involvement - seeding ... and Culture • CXR ... Tuberculosis Treatment ... • Check CXR and
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Lymphoma • Lung cancer ... involvement - seeding ... and Culture • CXR ... Tuberculosis Treatment ... • Check CXR and
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... can indicate disease ... microglobulin Treatment ... Transform to DLBCL, PML ... workup #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... Myeloproliferative Disease ... factor (GCSF) treatments ... Syndromes #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
number of sites of disease ... Hodgkin Lymphoma Treatment ... cycles without XR ... ABVD x 2 cycles + XR ... classification #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... Simultaneous clotting and bleeding ... interventional radiology ... “big & sticky” cells ... renal failure, pulmonary