19 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Malaise, bleeding ... night sweats, bleeding ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... transformation to acute leukemia ... only curative treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... microglobulin Treatment ... • Richter’s Syndrome ... • Sezary syndrome ... diagnosis #workup #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... diagnosis #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... lymphocytes, smudge cells ... immunophenotype Clinical ... #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... organ damage Clinical ... Schistocytes, helmet cells ... Treatment: ... diagnosis #causes #treatment
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... involved) • No leukemic ... Noncontiguous spread • Clinical ... Hepatosplenomegaly, cytopenias(bleeding ... NonHodgkins #comparison #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Release from blast cells ... Imaging: CXR- pulmonary ... management #hematology #oncology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Pathogenesis and clinical ... PO4& Mg prior to feeding ... - CHF - Pulmonary ... PO4 and Mg into cells