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diagnosis hematology cardiology causes nephrology table activetb algorithm cardiomyopathy classification criticalcare emergencies latenttb mds myelodysplastic oncologic peripartum pharmacology renal syndromes
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential ... Hyperviscosity Syndrome ... • Spontaneous bleeding ... neutrophil count < 500 cells ... #differential #
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... only curative treatment ... #treatment #hematology ... #oncology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... Liver diseases, Bleeding ... PD deficiency, Pulmonary ... Hemolytic uremic syndrome ... key #diagnosis #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... factor (GCSF) treatments ... blood count with differential ... diagnosis #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... hematology #diagnosis #management
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... adsorption onto cancer cells ... #treatment #hematology ... #differential
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Shock - Differential ... • Obstructive: Pulmonary ... Abdominal compartment syndrome ... Dehydration Shock Treatment ... #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC w differential ... capillaritis leading ... #differential # ... diagnosis #management ... #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... kidney tubular cells ... Rhabdomyolysis #Differential ... #Diagnosis #Management
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