10 results
Bleeding disorders in children

#Bleeding #Disorders #Differential #Hematology #Pediatrics #Peds
Bleeding disorders ... in children #Bleeding ... #Disorders #Differential ... #Hematology #Pediatrics ... #Peds
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Diagnosis Algorithm ... Hepatic vascular disorder ... (e.g. ascites), ... #Diagnosis #Algorithm ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Drug-induced Liver Injury ... dose dependent injury ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... Sequestration Disordered ... #Causes #Hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
PT (INR) - No Bleeding ... #PPT #PT #INR #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm
Congenital Anomaly / Disorder:
 •
Infancy (SUDI) - Differential ... Diagnosis Algorithm ... • Metabolic Disorders ... Gastrointestinal infection Injury ... #Causes #Peds #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... • Iatrogenic: DILI ... RBC (hemolysis, bleeding ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
RBC (hemolysis, bleeding ... Unconjugated Bili ... > 90% of Total Bili ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Disorders Age ... non-accidental injury ... #Bleeding #Disorders ... #History #peds ... pediatrics #diagnosis #hematology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Hepatitis - Management Algorithm ... blood, urine and ascites ... - Acute kidney injury ... HCV, DILI, HCC, ... #hepatology