57 results
Bleeding disorders in children

#Bleeding #Disorders #Differential #Hematology #Pediatrics #Peds
Bleeding disorders ... in children #Bleeding ... #Disorders #Differential ... #Hematology #Pediatrics
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Normal PT (INR) - Bleeding ... PT (INR) - No Bleeding ... #PPT #PT #INR #Differential ... Algorithm #Causes #Hematology ... #coagulation #disorders
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Sequestration Disordered ... Connective Tissue Disorders ... Algorithm #Causes #Hematology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome • Clinically ... suspect underlying hematologic ... disorders • Diagnosis ... and Treatment Algorithm ... Syndrome #HES #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... disorder Clinical ... • Prolonged bleeding ... factor VIII) Treatment ... Disease #Diagnosis #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... • Rheumatic disorders ... effect following treatment ... Thrombocytosis #Differential ... Algorithm #Causes #Hematology
Petechiae: punctate spots that arise from spontaneous bleeding secondary to profound thrombocytopenia. 
The spots (easily visible
from spontaneous bleeding ... UCSD Catalog of Clinical ... Images #Clinical ... #Photo #Dermatology ... #Rash #Petechiae
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... - History of bleeding ... epistaxis, gingival bleeding ... #Differential # ... Causes #Workup #hematology
Skin Hypopigmentation - Differential Diagnosis Algorithm

Diffuse Congenital - Generalized hypopigmentation of hair, eyes, skin
 • Phenylketonuria
Hypopigmentation - Differential ... sclerosis (white "ash ... Hypopigmentation #disorders ... #skin #dermatology ... #Differential #
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
Bleeding risk calculators ... validated for VTE treatment ... studies suggest net clinical ... with very high bleeding ... Anticoagulation #Factors #Hematology