10 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... • Systemic Lupus ... Leukemia - History of Bleeding ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE) Clinical ... autoantibodies that will cause ... inflammation, leading ... #neurology #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... nervous system (CNS ... purpura to mucosal bleeding ... SJIA], systemic lupus ... Treatment: • Corticosteroids
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Thromboembolism (7%) • CNS ... Treatment: ... Treat primary cause ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... and CNS • Headache ... Chronic B-cell activation
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... should be based on clinical ... Antimicrobial treatment ... Demyelinating disease caused ... #Infections #differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... by bleeding (petechiae ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... that results in CNS ... Transverse Myelitis - Clinical ... Transverse Myelitis Treatment ... management #neurology #differential
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management