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diagnosis rheumatology management erythematosus druginduced systemic activation approach arthritis cardiology cardiomyopathy cerebritis classification clues cns comparison cryoglobulinemia cryoglobulins dermatology dil
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... autoantibodies that will cause ... inflammation, leading ... Erythematosus #SLE
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... constitutional symptoms • Treatment ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
Sarcoidosis - Skin Manifestations This is a quick overview of some of the cutaneous manifestations of sarcoidosis.
Sarcoid Plaques • Lupus ... Sarcoidosis #diagnosis #clinical ... #differential # ... treatment #photo ... #dermatology #skinrash
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... 3) Limb oedema leading ... children (pediatric SLE ... #diagnosis #sle ... erythematosus #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... purpura to mucosal bleeding ... SJIA], systemic lupus ... erythematosus [SLE ... Treatment: • Corticosteroids
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... (e.g. systemic lupus
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... Like in this case ... get bacterial seeding ... Chronic = RA, SLE ... approach #workup #differential
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... is rare in DIL, SCLE-DIL ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Differential Diagnosis ... orthopnea, PND, LE ... support for patients clinically ... management #cardiology #treatment
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