13 results
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
Dermatoses: Sweet Syndrome ... dermatoses #skin ... #Rash #oncology ... #differential # ... diagnosis #cancer
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Tumor lysis syndrome ... lymphoid organs When Cancer ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Diagnosis Framework ... HEMATOLOGIC ... • Spontaneous bleeding ... diagnosis #cancer
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... , breast CA - Hematologic ... #diagnosis #dermatology ... #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... initiation • Differential ... #APML #diagnosis ... #management #hematology ... #oncology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... hemopathies, solid cancers ... #management #treatment
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
rash in association ... Resolution > 15 days Differentials ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Hepatomegaly • Skin ... • Richter’s Syndrome ... #workup #oncology ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... leukemia • Lung cancer ... • Cervical cancer
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... are caused by bleeding ... blood count with differential ... #diagnosis #hematology ... #oncology