13 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... Clinical • Easy bruising ... factor VIII) Treatment ... VonWillebrand #Disease ... #Diagnosis #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Coagulation #Bleeding ... #Bruising #Differential ... Algorithm #Causes #Hematology
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
Albumin Gradient ... the blood The diseased ... liverprof #Diagnosis #Hepatology ... Serum #Albumin #Gradient ... Interpretation #Differential
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
- Differential ... Veno-occlusive disease ... connective tissue disease ... #Differential # ... Diagnosis #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... ) estimated by gradient ... of portal HTN: ascites ... portal HTN: • Ascites ... Diagnosis #causes #hepatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Bleeding and Bruising ... of Hemostasis - Differential ... #Bruising #Hemostasis ... #Differential # ... Diagnosis #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
manifestations: from easy bruising ... purpura to mucosal bleeding ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
or venipuncture sites ... • Severe Liver Disease ... Treatment: ... diagnosis #causes #treatment ... #management #hematology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
over course of disease ... Infection, GI bleeding ... Initiate empiric treatment ... Encephalopathy #Grading ... #hepatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Easy or unusual bruising ... or bleeding, which ... Myeloproliferative Disease ... blood count with differential ... Syndromes #diagnosis #hematology