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diagnosis oncology management algorithm causes rheumatology deficiency pancytopenia workup bariatric bypass classification emergencies gastric gastroenterology hemeonc hepatology kidney leukemia nephrology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... telomeropathy Cancer ... consumption • Vitamin B12 ... #Diagnosis #Hematology
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Pregnancy, EPO treatment ... Loss (without anaemia ... Hookworm infection, Bleeding ... Iron #Deficiency #differential ... diagnosis #causes #nutrition
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
• Thiamine B1 ... Wernicke-Korsakoff syndrome ... gestation • Vitamin B12 ... Vitamins #Deficiency #differential ... signs #symptoms #nutrition
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
hemolytic-uremic syndrome ... crisis • Severe B12 ... macroangiopathic hemolytic anemia ... " • HELLP syndrome ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... - Low Serum B12 ... Myelodysplastic Syndromes ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... Liver diseases, Bleeding ... Hemolytic uremic syndrome ... key #diagnosis #differential ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
HLH syndrome 5. ... Drugs Nutritional ... Acquired Aplastic Anemia ... marrow failure syndrome ... Diagnosis #Algorithm #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Platelet Disorders • Nutritional ... : vitamin B12 or ... blood count with differential ... #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Kawasaki, Nephrotic syndrome
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
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