8 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels ... #lupus #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... inflammation, leading ... Erythematosus #SLE ... CNS #neurology #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... 3) Limb oedema leading ... children (pediatric SLE ... #diagnosis #sle ... erythematosus #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... other medications leading ... Risks #Benefits #Lupus ... #pharmacology # ... #sideeffects #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... (e.g. systemic lupus ... classification #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
spondyloarthropathies, lupus ... Like in this case ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology #
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... : neuro, heme (bleeding ... Better call hematology ... some time, let’s see ... Algorithm #workup #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology