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rheumatology treatment differential algorithm lupus workup blood classification dermatology erythematosus hepatology product reactions summary syndrome systemic achalasia activation approach arthritis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... - History of bleeding ... PT, aPTT(liver disease ... test, ANA (e.g., SLE ... #hematology
Upper GI Bleed - Management Algorithm Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR Initial Stabilization Concern for
Upper GI Bleed - Management ... Consult GI ± EGD Causes ... • Variceal Bleeding ... #Differential #Diagnosis ... gastrointestinal #gastroenterology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... screening for disease ... with established disease ... normal in mild cases ... #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Positive in 60-80% of cases ... : Chronic disease ... Erythematosus #Diagnosis ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Usual therapeutic management ... : Chronic disease ... #comparison #table ... #rheumatology # ... diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... autoantibodies that will cause ... inflammation, leading ... #management #treatment
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Severe Liver Disease ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... erythematosus [SLE ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... night sweats, bleeding ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment ... #summary #rheumatology
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