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management rheumatology sle treatment activation algorithm anemia aplastic bilirubin cerebritis classification coagulation comparison congenital cryoglobulinemia cryoglobulins dic differential diffuse disseminated
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... • Systemic Lupus ... Leukemia - History of Bleeding ... #Hematology #Oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE) Clinical ... autoantibodies that will cause ... inflammation, leading ... #neurology #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... Thromboembolism (7%) • CNS ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... leukostasis syndrome: CNS ... #Leukemia #Hematology ... #Oncology #Diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... Fever is the main clinical ... nervous system (CNS ... SJIA], systemic lupus ... Activation #Syndrome #Diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... (e.g. systemic lupus
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
as jaundice on clinical ... 7-20 mg/dL • CN ... and stress may cause ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
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