19 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... disease Palpable purpura ... Henoch Schönlein purpura ... lesions • Discoid lupus ... #rashes #differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Splenomegaly - CTD (SLE ... Associated - SLE ... #Differential # ... Diagnosis #hematology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
correlations • Purpura ... Identification of causes ... disease (10%) : SLE ... (5%): PAN > GPA ... pathology #lesions #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... tract, and often causes ... such as systemic lupus ... , and SLE) • Urinalysis ... #rheumatology #
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... erythematosus (SLE ... #Diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... (SLE) General: ... Butterfly rash, Vasculitis ... , Purpura, Urticaria ... lesions Abdominal pain
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... (e.g. systemic lupus ... erythematosus (SLE
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Infection - Vasculitis ... lesions • Severe pain ... (lupus, RA, Sjogren's
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Henoch-SchonIein Purpura ... Glomerulonephritis #Vasculitis ... #differential #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... burning sensation or pain ... reticularis Differential ... Polyangiitis #GPA #dermatology ... rash #diagnosis #rheumatology