14 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... #differential #Diagnosis ... #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
Abnormal renal/liver ... >2.3mg/dL) 1 Liver ... S Stroke 1 B Bleeding ... Anticoagulation #AFib #Diagnosis ... #Hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... Injury (DILI) ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis ... disorder (e.g. ascites ... #Injury #Diagnosis ... #Algorithm #hepatology
Spontaneous Bacterial Peritonitis (SBP) - Diagnosis and Management
Ascites PMN > 250/mm3
? Nosocomial or hospital acquired. Recent
Peritonitis (SBP) - Diagnosis ... and Management Ascites ... acceptable Upper Gl bleeding ... dysfunction or liver ... #Management #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... RBC (hemolysis, bleeding ... #differential #diagnosis ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
injury < 26 weeks ... hepatocellular injury ... RBC (hemolysis, bleeding ... #chemistry #diagnosis ... #differential #Hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Findings: • Bleeding ... or venipuncture sites ... DIC • Severe Liver ... #Coagulation #diagnosis ... treatment #management #hematology
VIBES Mnemonic - Cirrhosis Management Checklist

V - Volume (Ascites, HRS)
	- Evaluate for Ascites, Edema, Hydrothorax, Hepatorenal
V - Volume (Ascites ... bactrim or FQ B - Bleeding ... - Ppx (non-bleeding ... Mnemonic #Management #Diagnosis ... #Hepatology #Gastroenterology
Common Malignancies That Cause Ascites
The most common malignancies causing ascites are ovarian cancer, pancreatic cancer, gastric
is peritoneal seeding ... or liver metastases ... peritoneum or liver ... #Differential #Diagnosis ... #Hepatology #oncology