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management anemia differential causes oncology algorithm product reactions anticoagulation approach bariatric bypass calculation calculators cancer chronic classification cll coagulation complications
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... Symptomatic anemia Diagnosis ... #Anemia #diagnosis ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Loss • Acute Bleed ... Deficiency • Aplastic ... Algorithm #Causes #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
Bleeding risk calculators ... - HAS-BLED (atrial ... validated for VTE treatment ... Anticoagulation #Factors #Hematology ... #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... anemia Treatment ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... marrow failure: Aplastic ... loss: Trauma, Gl bleed ... Production #Index #hematology ... #differential #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... Treatment: ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... Causes • Anemia • Aplastic ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Lymphocytosis: Absolute blood ... Pure red cell aplasia ... microglobulin Treatment ... workup #oncology #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... due to marrow aplasia ... coagulopathy & ↑bleeding ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Injury (TRALI): Leading ... due to marrow aplasia ... coagulopathy & ↑bleeding ... #Transfusions #diagnosis ... #management #hematology
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