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differential management algorithm coagulation oncology prolonged abnormal disorders pt rheumatology treatment workup ascites blood joint liver pain product reactions thrombocytopenia
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
: Is the PT or APTT ... K Antagonists, Heparin ... to identify the cause ... #prolonged #diagnosis ... #hematology #evaluation
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PT (INR) - No Bleeding ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation
Disorders of the Hepatic and Mesenteric Circulation Platelets in Cirrhosis Hypercoagulability in Cirrhosis Bleeding in Cirrhosis Portal Vein Thrombosis (PVT) Mesenteric
Disorders of the Hepatic ... in Cirrhosis Bleeding ... Circulation #Disorders #Hepatology ... #Gastroenterology ... #diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
deficiency) • HIT ... INR < 2.3 - APTT ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... - History of bleeding ... epistaxis, gingival bleeding ... : INR/PT, aPTT(liver ... #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... thrombin inhibitors, heparin ... #diagnosis #differential ... #hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... e.g. heparin ... #diagnosis #differential ... #hematology #coagulation
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis ... established disease) • aPTT ... mixing study (aPTT ... normal in mild cases ... Management #treatment #hematology
4-T Score for the Likelihood of Heparin Induced Thrombocytopenia - Thrombocytopenia - Compare the highest platelet count
Likelihood of Heparin ... Other potential cause ... #Heparin #Induced ... Thrombocytopenia #Likelihood #Diagnosis ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... • CMV • HIV ... Leukemia - History of Bleeding ... #Hematology #Oncology
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