50 results
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
- Differential Diagnosis ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct #bilirubin ... #Algorithm #gastroenterology ... #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... Phosphatase and Bilirubin ... initial insult Bilirubin ... #Hepatology #Pathophysiology ... #Diagnosis #LFTs
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
in bone Total bilirubin ... TBili) Direct bilirubin ... Indirect bilirubin ... Interpretation #diagnosis ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
week • Direct bilirubin ... Elevation: • Bilirubin ... RBC (hemolysis, bleeding ... #chemistry #diagnosis ... #differential #Hepatology
Cirrhosis leading to Chronic Liver Failure - Clinical Signs and Symptoms

#Cirrhosis #LiverFailure #Signs #Symptoms #PhysicalExam #Findings
Cirrhosis leading ... to Chronic Liver ... PhysicalExam #Findings #Diagnosis ... #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... week • Direct bilirubin ... RBC (hemolysis, bleeding ... #differential #diagnosis ... #algorithm #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
fold elevation, Bilirubin ... fold elevation, Bilirubin ... but variable ++, Bilirubin ... Disease #Pregnancy #hepatology ... #differential #diagnosis
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
Abnormal renal/liver ... (cirrhosis, bilirubin ... S Stroke 1 B Bleeding ... Anticoagulation #AFib #Diagnosis ... #Hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
of hemolysis or liver ... birth with serum bilirubin ... associated with bilirubin ... #hepatology #diagnosis ... #gastroenterology
Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Stabilization Concern for Liver ... Disease • Variceal Bleeding ... GAVE (idiopathic, liver ... #Differential #Diagnosis ... gastrointestinal #gastroenterology