13 results
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
- Differential Diagnosis ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct #bilirubin ... #Algorithm #gastroenterology ... #hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... 80-100 fL) • Bleeding ... Renal Disease, Liver ... #Anemia #MCV #Classification ... Algorithm #Causes #Hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
week • Direct bilirubin ... Elevation: • Bilirubin ... RBC (hemolysis, bleeding ... #chemistry #diagnosis ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... week • Direct bilirubin ... RBC (hemolysis, bleeding ... #differential #diagnosis ... #algorithm #hepatology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
Abnormal renal/liver ... (cirrhosis, bilirubin ... S Stroke 1 B Bleeding ... Anticoagulation #AFib #Diagnosis ... #Hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
of hemolysis or liver ... birth with serum bilirubin ... associated with bilirubin ... #hepatology #diagnosis ... #gastroenterology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
the spleen or liver ... translocation • Types: Classification ... Hepatosplenomegaly, cytopenias(bleeding ... NonHodgkins #comparison #oncology ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
purpura to mucosal bleeding ... thrombocytopenia • Liver ... ↑ AST ↑ ALT ↑ bilirubin ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
in lung>heart>liver ... symptoms, unexplained hematologic ... and classification ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
Encephalopathy - Diagnosis ... • Caused by liver ... Infection, GI bleeding ... Encephalopathy #Grading #Classification ... #treatment #hepatology