9 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome • Clinically ... disordersDiagnosis ... and Treatment Algorithm ... Syndrome #HES #Hematology ... #management #algorithm
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... Sequestration Disordered ... #Hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
PT (INR) - No Bleeding ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation ... #disorders
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... disorder Clinical ... • Prolonged bleeding ... VonWillebrand #Disease #Diagnosis ... #Hematology
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
amyloidosis, or related disorder ... pain, abnormal bleeding ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology ... #Diagnosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Paradoxical spontaneous bleeding ... cryoglobulinemia Associated Disorders ... : • + Clinical ... Biopsy: Typical pathologic ... hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... Disorders Age ... #Bleeding #Disorders ... peds #pediatrics #diagnosis ... #hematology #primarycare
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
current treatment algorithm ... median age at diagnosis ... an infection or bleeding ... importance of clinical ... #algorithm #hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
plasmacytoma) Clinical ... Diagnosis? ... Biopsy: Solitary disorder ... IFE, FLC assay Pathology ... #Workup #Hematology