12 results
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... #Rouleaux #formation ... gammopathy #MGUS #Clinical ... #Pathology #Hematology ... #Smear
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
extensive rouleaux formation ... leukemia #rouleaux #formation ... #Clinical #Smear ... #Hematology #Pathology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... DIC, TTP, HUS) ... Peripheral #Blood #Smear ... #Analysis #hematology ... interpretation #clinical
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation (DIC ... organ damage Clinical ... • Peripheral smear ... significant fibrin clot formation ... treatment #management #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation (DIC ... accelerate thrombin formation ... reactant Blood smear ... small vessels #DIC ... Scoring #diagnosis #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... arrow) Peripheral smear ... hemolytic #anemia #Hematology ... #Pathology #Smear
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Differential Diagnosis Algorithm ... Normal Blood Smear ... RBCs in Rouleaux Formation ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
from “Rouleaux formation ... #Clinical #Pathology ... #Blood #Smear # ... Microscopy #Rouleaux #Formation ... #Hematology
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
pain, abnormal bleeding ... ) • Rouleaux formations ... peripheral blood smear ... Electrophoresis #SPEP #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... • Peripheral smear ... • Significant bleeding ... Fibrinolysis & DIC ... #Leukemia #Hematology