12 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Idiopathic Thrombocytopenic ... Purpura Clinical ... Menorrhagia • GI bleeding ... only for severe bleeding ... Diagnosis #Overview #Hematology
Petechiae: punctate spots that arise from spontaneous bleeding secondary to profound thrombocytopenia. 
The spots (easily visible
from spontaneous bleeding ... Images #Clinical ... #Photo #Dermatology ... #Rash #Petechiae ... #Thrombocytopenia
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Heparin-Induced Thrombocytopenia ... Suspected HIT Algorithm ... • "4 T's" clinical ... #HIT #hematology ... diagnosis #4Ts #algorithm
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... disorder Clinical ... • Prolonged bleeding ... platelet count (mild thrombocytopenia ... Disease #Diagnosis #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Thrombocytopenia ... Coagulation #Bleeding ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
transfusion • Thrombocytopenia ... organ damage Clinical ... DITMA) - MAHA + Thrombocytopenia ... coagulopathy - Thrombocytopenia ... treatment #management #hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
based primarily on clinical ... Estimates of the clinical ... Diagnosis #Management #Hematology ... Heparin #Induced #Thrombocytopenia ... #Algorithm
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... Petechial or purpuric rash ... leukopenia, anemia, and thrombocytopenia ... Diagnosis #Management #Hematology ... #Rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... infections/fevers • Thrombocytopenia ... ecchymoses, mucosal bleeding ... Anemia #oncology #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... purpura & severe thrombocytopenia ... Injury (TRALI): Leading ... coagulopathy & ↑bleeding ... diagnosis #management #hematology