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management anemia aplastic oncology syndrome activation algorithm anticoagulation calculators cancer causes clinical coagulation deficiency dic differential disease disseminated factors finger
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... • Prolonged bleeding ... factor VIII) Treatment ... VonWillebrand #Disease #Diagnosis ... #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
Bleeding risk calculators ... validated for VTE treatment ... with very high bleeding ... Anticoagulation #Factors #Hematology ... #Diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
neutropenia • Mucosal bleeding ... Symptomatic anemia Diagnosis ... megaloblastic anemia Treatment ... #management #treatment ... #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis ... Classify severity Treatment ... by a hemophilia treatment ... #Management #treatment ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Findings: • Bleeding ... Treatment: ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
hemolytic anemia, or psoriasis ... interfered with leading ... #differential #diagnosis ... #hematology #nutrition
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
pustulosis, pustular psoriasis ... , psoriasis vulgaris ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #Dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... factor (GCSF) treatments ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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