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diagnosis oncology management algorithm differential leukemia workup activation aplastic causes chronic cll disorders hemeonc hemophagocytic hlh lymphocytic lymphohistiocytosis macrophage mas
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... , and petechiae ... (MDS) (normal or ... result from low blood ... #oncology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... hemolysis, deficiency anemia ... Malignancy: Metastatic cancer ... Diagnosis #Algorithm #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... unusual bruising or bleeding ... are caused by bleeding ... (petechiae) • ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... (Petechial or purpuric ... rash) • Heart, ... with leukopenia, anemia ... Diagnosis #Management #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... (petechiae, ecchymoses ... plateletcount), peripheral blood ... changes), high MCV anemia ... Causes #Workup #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Significant ↓ PLT: Petechiae ... - infiltrates (anemia ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... #Leukemia #Hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... , breast CA - Hematologic ... neutrophils in the blood ... #diagnosis #dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Physical Exam/Signs ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... workup #oncology #hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... From Blood Cancer ... disease tolerate anemia ... an infection or bleeding ... #algorithm #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
it is often a cancer ... (often termed MAS-HLH ... Presentation • Common Signs ... - Cytopenias (anemia ... Diagnosis #Management #Hematology
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