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diagnosis rheumatology anemia aplastic blood differential oncology product reactions activation algorithm antinxp2 antinxp2dm autoimmune comparison dermatomyositis erythematous febrile fever leukostasis
DRESS Syndrome vs SJS/TEN DRESS • Latency: 2-8 weeks • Rash: Morbilliform • Mucosal involvement: 50% have
DRESS Syndrome vs ... : 2-8 weeks • Rash ... involvement with bleeding ... #Syndrome #SJS ... comparison #table #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Systemic Symptoms (DRESS ... extensive skin rash ... eruption that may ... SinaiBmoreIMRes #DRESS ... #Syndrome #dermatology
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
and toxic shock syndrome ... erythematous rash ... may be having ... #Diagnosis #Dermatology ... #Erythematous #Rash
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... Petechial or purpuric rash ... Plasma exchange #MAS ... #Diagnosis #Management ... #Hematology #Rheumatology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... neutropenia • Mucosal bleeding ... Can progress to MDS ... Anemia #diagnosis #management ... #treatment #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... , breast CA - Hematologic ... #diagnosis #dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... Constitutional Syndromes ... Anemia #oncology #hematology ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... : - Neuro: AMS ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Injury (TRALI): Leading ... coagulopathy & ↑bleeding ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
maculopapular rash ... Injury (TRALI): Leading ... coagulopathy & ↑bleeding ... Transfusions #diagnosis #management ... #hematology #reactions
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