11 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... common inherited bleeding ... disorder Clinical ... VonWillebrand #Disease ... #Diagnosis #Hematology
Scleroderma Associated Telangiectasia. 

If you see them-round, often well circumscribed (but can be matte-like too) &
Telangiectasia #clinical ... #video #blanching ... #skin #dermatology ... #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... Noncontiguous spread • Clinical ... Hepatosplenomegaly, cytopenias(bleeding ... Lymphomas • Other hematologic ... #differential #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Paradoxical spontaneous bleeding ... Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Findings: • Bleeding ... organ damage Clinical ... Findings: • Bleeding ... • Severe Liver Disease ... treatment #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... purpura to mucosal bleeding ... Diagnosis #Management #Hematology ... #Rheumatology
Von Willebrand Disease Classification
Type 1 (Accounts for ~3/4 of cases):
 • Defect: Quantitative defect (i.e. not
Von Willebrand Disease ... (uncommon) • Bleeding ... : Severe (Clinically ... VonWillebrand #Disease ... Types #diagnosis #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... in Evaluating Bleeding ... von Willebrand disease ... von Willebrand disease ... pediatrics #diagnosis #hematology
Blanching Spider Angioma (Nevus) on Physical Exam

Spider angiomas are usually benign but often can be suggestive
Blanching Spider ... underlying systemic disease ... #PhysicalExam #clinical ... #video #dermatology ... #skin #blanching
Monkeypox Skin Rash
30 yr F and her 6 yr daughter purchased 2 prairie dogs 10 days
, contaminated bedding ... University Infectious Diseases ... #Monkeypox #SkinRash ... #clinical #photo ... #dermatology