11 results
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology ... #Interactions #Table
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... bruising • Skin ... bleeding from mucosal ... factor VIII) Treatment ... Disease #Diagnosis #Hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
at high risk of bleeding ... interactions and bleeding ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... distinction has HUGE treatment ... and first-line treatment ... Comparison #Diagnosis #Table ... #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Scleroderma Associated Telangiectasia. 

If you see them-round, often well circumscribed (but can be matte-like too) &
& blanchable, differential ... Telangiectasia #clinical #video ... #blanching #skin ... #dermatology #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
glucocorticoid treatment ... symptoms (eg, skin ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
arterial thrombosis, skin ... exposure (prevent skin ... , Bivalirudin, DOAC ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... the mainstay of treatment ... #Scleroderma #Differential ... Diagnosis #comparison #table ... #dermatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... ecchymoses, mucosal bleeding ... aplastic anemia Treatment ... Anemia #oncology #hematology