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management algorithm oncology aplastic cancer hasbled risk thromboembolism venous activation afib bleed calculators chads2 chads2vasc comparison doac dvt factors improve
Venous Thromboembolism Treatment Algorithm Branch points: Active bleeding? Active malignancy? Provoked? - Dr. Joseph Shatzel @Clotmaster #Management #VTE #DVT
Thromboembolism Treatment ... points: Active bleeding ... #Management #VTE ... Thromboembolism #Treatment ... #Hematology #Anticoagulation
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
) and IMPROVE (VTE ... validated for VTE ... treatment, only ... #Factors #Hematology ... #Diagnosis
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
for VTE in Malignancy ... at high risk of bleeding ... risk of recurrent VTE ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
neutropenia • Mucosal bleeding ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... #diagnosis #management ... #treatment #hematology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation C Congestive Heart Failure 1 H Hypertension 1 A2 Age >75 2 D Diabetes Mellitus 1 S2 Stroke,
bleed risk on anticoagulation ... S Stroke 1 B Bleeding ... history/anemia ... #AFib #Diagnosis ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... ecchymoses, mucosal bleeding ... Treatment: ... #oncology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Longterm Venous Thromboembolism Treatment Algorithm Treat for 3 months and reassess • Isolated distal DVT (without cancer)
Thromboembolism Treatment ... PE - High Bleeding ... therapy - Second VTE ... Algorithm #management #hematology ... #anticoagulation
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... factor (GCSF) treatments ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... median age at diagnosis ... disease tolerate anemia ... an infection or bleeding ... #algorithm #hematology
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