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diagnosis management oncology anticoagulation algorithm doac dvt malignancy thromboembolism venous anemia aplastic atopic atopy calculators chemotherapy classification coagulation cyp3a4 damage
Venous Thromboembolism Treatment Algorithm Branch points: Active bleeding? Active malignancy? Provoked? - Dr. Joseph Shatzel @Clotmaster #Management #VTE #DVT
Thromboembolism Treatment ... points: Active bleeding ... #Management #VTE ... Thromboembolism #Treatment ... #Hematology #Anticoagulation
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
for VTE in Malignancy ... thrombosis in cancer ... risk of recurrent VTE ... #Cancer #Algorithm ... Anticoagulation #Management #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
Bleeding risk calculators ... ) and IMPROVE (VTE ... validated for VTE ... treatment, only ... Anticoagulation #Factors #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... of cancer-associated ... body mass index; VTE ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
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 Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... Classify severity Treatment ... by a hemophilia treatment ... center. ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Treatment: ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Longterm Venous Thromboembolism Treatment Algorithm Treat for 3 months and reassess • Isolated distal DVT (without cancer)
Thromboembolism Treatment ... PE - High Bleeding ... - Not High Bleeding ... therapy - Second VTE ... Algorithm #management #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology
Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism https://www.nejm.org/doi/full/10.1056/NEJMoa1711948 Authors’ Conclusions: “Oral edoxaban was noninferior to subcutaneous dalteparin
Edoxaban for the Treatment ... of Cancer-Associated ... respect to recurrent VTE ... observed in all-cause ... VenousThromboembolism #VTE
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... cancer such as ... Treatment: - Systemic ... Syndrome #diagnosis #dermatology
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