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anticoagulation management algorithm oncology pharmacology cancer diagnosis dvt malignancy oral thromboembolism venous apixaban bridging calculators causes chemotherapy coagulation cyp3a4 dabigatran
Oral anticoagulant dosing and bridging for VTE - Dr. Joseph Shatzel @Clotmaster #VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... and bridging for VTE ... Clotmaster #VTE ... #DOAC #Bridging ... #Pharmacology #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... direct-acting oral anticoagulants ... body mass index; VTE ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
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 Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
for VTE in Malignancy ... risk of recurrent VTE ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
Venous Thromboembolism Treatment Algorithm Branch points: Active bleeding? Active malignancy? Provoked? - Dr. Joseph Shatzel @Clotmaster #Management #VTE #DVT
Thromboembolism Treatment ... points: Active bleeding ... #Management #VTE ... Thromboembolism #Treatment ... #Hematology #Anticoagulation
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
DOAC Reversal Emergency ... procedure Stop anticoagulant ... treatment; volume ... #Oral #anticoagulant ... #hematology #management
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
Bleeding risk calculators ... ) and IMPROVE (VTE ... validated for VTE ... treatment, only ... Anticoagulation #Factors #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Findings: • Bleeding ... Reduction of pro/anticoagulants ... Treatment: ... diagnosis #causes #treatment ... #management #hematology
Longterm Venous Thromboembolism Treatment Algorithm Treat for 3 months and reassess • Isolated distal DVT (without cancer)
Thromboembolism Treatment ... PE - High Bleeding ... - Not High Bleeding ... therapy - Second VTE ... Algorithm #management #hematology
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