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diagnosis differential algorithm causes oncology workup management classification hemolytic leukemia testing atlas disease hemolysis laboratory lymphocytic morphology rbc rheumatology abg
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... #Disorders #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Unstable hemoglobin disorders ... , Paroxysmal cold ... differential #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... blast cells - Blood ... - infiltrates (anemia ... #Leukemia #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... Immunoglobulin M (IgM) • Blood ... malignancies -> CLL ... sensitize red blood ... #hematology #diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... RBCs on Smear • Chronic ... • Anemia of Chronic ... • RBC Membrane Disorder ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
practices that could ... plateletcount), peripheral blood ... changes), high MCV anemia ... not required in all ... Causes #Workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) (e.g. lupus, CLL ... (e.g. primary cold ... lymphoproliferative disorders ... differential #diagnosis #hematology ... #anemia
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... hemorrhage) • Chronic ... inflammatory disorders ... myeloid leukemia (CML ... Diagnosis #Causes #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Iron-deficiency anemia ... cells - Sickle cell ... Liver diseases, Bleeding ... #differential #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... blood loss), Vitamin ... deficiencies: Chronic ... defects (e.g. sickle cell ... Production #Index #hematology
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