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diagnosis oncology product reactions rheumatology treatment anemia aplastic cerebritis coagulation cryofibrinogenemia differential disseminated eosinophils erythematosus hes hypereosinophilia intravascular leukemia lupus
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Diagnosis and Management ... with blood eosinophilia ... Secondary Causes ... : - Allergic disorders ... #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... Thromboembolism (7%) • CNS ... Treat primary cause ... #treatment #management ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... , Seizure disorders ... autoantibodies that will cause ... thrombosis and/or blood-brain ... cerebritis #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... • (Peripheral eosinophilia ... Fibrinolysis & DIC ... #Leukemia #Hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
which can plug blood ... Paradoxical spontaneous bleeding ... cryoglobulins • Negative causes ... skin necrosis • DIC ... #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... Causes purpura & ... cause of transfusion ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... Causes purpura & ... cause of transfusion ... Transfusions #diagnosis #management ... #hematology #reactions
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
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