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diagnosis differential algorithm causes leukemia management atlas classification disorders lymphocytic morphology workup aplastic approach bloodcell calculation elevatedmcv hemeonc hepatitis hodgkins
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... anemia, Chronic ... disease, McLeod blood ... Bite Cell RBC: G6PD ... differential #diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... on Smear • Chronic ... • B12/Folate Deficiency ... • Anemia of Chronic ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... Liver diseases, Bleeding ... coagulopathy (DIC) #RBC ... #differential #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... , Intrinsic RBC ... defects (e.g. sickle cell ... anemia, G6PD deficiency ... Production #Index #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC ... #Disorders #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
>13 • Iron Deficiency ... (Eg Causes: Chronic ... Blood Loss, Occult ... Malabsorption, Dietary Deficiency ... Algorithm #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... , GATA2 deficiency ... Pancytopenia: • ↓ RBC ... result from low blood ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... are caused by bleeding ... Marrow Failure • Chronic ... Syndromes #diagnosis #hematology ... #oncology
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