16 results
diagnosis differential leukemia management workup algorithm atlas causes chronic disorders hemolytic lymphocytic morphology agglutinin aplastic bloodcell calculation cell classification cold
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Bite Cell RBC: G6PD ... IgM associated lymphoma ... differential #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... Liver diseases, Bleeding ... coagulopathy (DIC) #RBC ... #differential #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... blast cells - Blood ... - infiltrates (anemia ... #Hematology #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... , Auer rod • Lymphoid ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC ... #Disorders #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... , Intrinsic RBC ... defects (e.g. sickle cell ... anemia, G6PD deficiency ... Production #Index #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) (e.g. lupus, CLL ... , lymphoma, idiopathic ... • Intrinsic RBC ... G6PD deficiency) ... differential #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... , GATA2 deficiency ... Pancytopenia: • ↓ RBC ... result from low blood ... #oncology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
autoimmune disorder or lymphoid ... - Monoclonal - Lymphoid ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... #hematology #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... plateletcount), peripheral blood ... changes), high MCV anemia ... not required in all ... Causes #Workup #hematology
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