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diagnosis management algorithm cancer malignancy mds myelodysplastic vte anemia aplastic calculators cell chemotherapy cyp3a4 emergencies factors hasbled hemeonc inducers inhibitors
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
Bleeding risk calculators ... fibrillation) and IMPROVE ... validated for VTE treatment ... #IMPROVE #Bleeding ... #Factors #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
Patient risk stratification ... algorithm for the treatment ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
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 Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
DOAC, direct oral ... #DOAC #VTE #Malignancy ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
) Cancer-treatment ... thereby leading ... metabolization leading ... #Chemotherapy #Oncology ... #Hematology #Interactions
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
diagnosis and risk-stratification ... • Risks: infection ... Hypomethylating agents to improve ... only curative treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... aplastic anemia Treatment ... : • Improve the ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Longterm Venous Thromboembolism Treatment Algorithm Treat for 3 months and reassess • Isolated distal DVT (without cancer)
Thromboembolism Treatment ... PE - High Bleeding ... - Not High Bleeding ... Algorithm #management #hematology ... #anticoagulation
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... syndrome): - Hematologic ... mg/dL or > 25 % rise ... Simultaneous clotting and bleeding ... stenting - Consider anticoagulation
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... carries a variable risk ... Syndromes #diagnosis #hematology ... #oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Bone marrow Treatment ... associated with improved ... involvement - higher risk ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
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