38 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Malaise, bleeding ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... Physical Exam/Signs ... Diagnosis: • ... and other C Cell ... workup #oncology #hematology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Stevens-Johnson Syndrome ... differentiating between the diagnosis ... #TEN #Dermatology ... #PhysicalExam # ... Video #Clinical
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... neutropenia • Mucosal bleeding ... Symptomatic anemia Diagnosis ... Consider stem cell ... management #treatment #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... - History of bleeding ... K), H. pylori test ... not required in all ... Causes #Workup #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... the critically ill ... Elevated Liver tests ... AFLP #obstetrics #hematology ... #diagnosis #table
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
IL-6, leading to ... purpura to mucosal bleeding ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... malignancies -> CLL ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... NO prior signs ... - **MSK rads ... • PVNS/Giant Cell ... #msk #rheumatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... the critically ill ... Elevated Liver tests ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison