9 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE) Clinical ... prevention (statin for CVA ... #neurology #rheumatology ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... purpura to mucosal bleeding ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... +GI+CVS+joints) ... • Amyloidosis (CVS ... to cold IgG • Lupus
Indications for tPA in Stroke:
 • Clinical diagnosis of ischemic stroke
 • Measurable neurologic deficit
 •
in Stroke: • Clinical ... diagnosis of ischemic ... Active internal bleeding ... #tPA #Stroke #cva ... #management #neurology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Thromboembolism (7%) • CNS ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... may precede the neurologic ... PRES-Associated Clinical ... narrowing on MRA/CTA ... #management #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... skin injury) • Neurologic ... Behcet syndrome (Clinical ... #management #signs ... #symptoms #rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... has five major clinical ... especially the CNS ... MC: CNS CSF: • ... #Management #Infections