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hematology diagnosis oncology leukemia management mds myelodysplastic algorithm calculation chronic differential index lymphocytic myelodysplasia production reticulocyte syndrome syndromes workup
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... stem cell transplant ... progress to MDS or acute ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... is of B-cell lineage ... - infiltrates (anemia ... lymphoid organs When Cancer
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
maturation factor is ... marrow failure: Aplastic ... infiltration (e.g. cancer ... Index > 3: • Acute ... defects (e.g. sickle cell
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... transformation to acute ... Allogeneic stem cell ... transplant is only
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... • Neutropenia, anemia ... aplasia • ITP ... microglobulin Treatment ... ’s lymphoma or acute
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... • Aplastic Anemia ... factor (GCSF) treatments ... Syndromes #diagnosis #hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... clonal evolution to acute ... disease tolerate anemia ... with repeated red cell ... an infection or bleeding
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