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Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign")

Asboe-Hansen sign is the extension
margin around the bulla ... generate a fresh bulla ... for lesional skin ... Video #Clinical #Bullae ... #Dermatology #skin
Vibrio vulnificus Infection- At the time of presentation, hemorrhagic bullae measuring 3.5 by 4.5 cm had
presentation, hemorrhagic bullae ... confluent tense bullae ... isolated from the bullae ... vulnificus can cause skin ... vibrio #vulnificus #bullae
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma

DRESS 
 - Onset:
dermattiis, tense bullae ... - Features: Bullae ... pustules, tense bullae ... >90% of total skin
Pruritus - Primary Skin Lesion - Differential Diagnosis Algorithm
Macules / Papules / Plaques:
 • Xerosis (dry
Pruritus - Primary Skin ... • Xerosis (dry skin ... bites Vesicles/Bullae
Reactive Skin Rash - Differential Diagnosis Algorithm
Reactive erythematous with various morphology
 • Urticaria - Firm /
Reactive Skin Rash ... vesicles &/or bullae
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Causes == Primary Skin ... • Xerosis (dry skin ... bites Vesicles/Bullae ... == No Primary Skin
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Involving the Skin ... Vasculitis Skin ... purpura, Hemorrhagic bullae ... Cutaneous #Vasculitis #skin
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
Tubulointerstitial nephritis • Skin ... centers → vesicles/bullae ... Prerenal azotemia • Skin
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin ... • Diabetic bullae
Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign")

Update View High-Res Mp4 Video
margin around the bulla ... generate a fresh bulla ... for lesional skin