18 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Pathophysiology ... Differentiation #Syndrome ... #APML #diagnosis ... #management #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Diagnosis Framework ... 2nd pass = Chronic ... Eosinophilic GI Disorders ... cell activation syndrome ... #Diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... Cold Agglutinin Syndrome ... infection, autoimmune disorder ... IgM Includes Disorders ... hemolytic #anemia #hematology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Neurocognitive Disorder ... Neurocognitive disorders ... • Movement disorders ... The clinical syndrome ... neurocognitive #disorder
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... age 70 years Symptoms ... Marrow Failure • Chronic ... Neutropenia • Platelet Disorders ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... lymphoproliferative disorders ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... dermatosis (Sweets Syndrome ... Rare Disorder: ... classical Sweet syndrome ... #diagnosis #dermatology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
, Loose anagen syndrome ... levels Systemic Disorders ... • Thyroid disorders ... • Hormonal disorder ... #Diagnosis #dermatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
an autoimmune disorder ... thyroid, Sjogren syndrome ... “dropping head syndrome ... - Kearns-Sayre syndrome ... Eaton myasthenia syndrome
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) • Endocrine disorders ... lymphoma • Evans' syndrome ... Shrinking lung syndrome ... dysfunction, and mood disorder ... endocarditis • Valvular disorders