15 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... Cold Agglutinin Syndrome ... infection, autoimmune disorder ... IgM Includes Disorders ... hemolytic #anemia #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Pathophysiology ... Differentiation #Syndrome ... #APML #diagnosis ... #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... age 70 years Symptoms ... Marrow Failure • Chronic ... Neutropenia • Platelet Disorders ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... lymphoproliferative disorders ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) • Endocrine disorders ... lymphoma • Evans' syndrome ... Shrinking lung syndrome ... dysfunction, and mood disorder ... endocarditis • Valvular disorders
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... dermatosis (Sweets Syndrome ... Rare Disorder: ... classical Sweet syndrome ... #diagnosis #dermatology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
, Loose anagen syndrome ... levels Systemic Disorders ... • Thyroid disorders ... • Hormonal disorder ... #Diagnosis #dermatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... tests in Behcet syndrome ... ) Differential Diagnosis ... adenopathy (PFAPA) syndrome ... #signs #symptoms
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... and signs below ... MCTD, Sjogren syndrome ... cord #spinalcord #disorders ... #diagnosis #neurology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
TAFRO TAFRO syndrome ... which is a rare disorder ... - Autoimmune disorders ... - Infectious disorders ... and the systemic symptoms