15 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... Agglutinin Syndrome ... infection, autoimmune disorder ... IgM Includes Disorders ... hemolytic #anemia #hematology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... Spinal cord ... and signs below ... #spinalcord #disorders ... #diagnosis #neurology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Thrombocytopenia and Platelet Disorders ... pylori test (GI symptoms ... disorder is suspected ... Thrombocytopenia #Platelet #Disorders ... #Workup #hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Focal inflammatory disorder ... and/or symptoms ... , MOG antibody disorders ... (MOG) antibody disorders ... • Inflammatory Disorders
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Pathophysiology ... : >3 symptoms, or ... initiation • Differential ... #APML #diagnosis ... #management #hematology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... impairment, Mood disorder ... Signs and symptoms ... Progressive MS (Spinal cord ... #treatment #MS
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogen is a cold ... - Albumin - Cold ... cryoglobulinemia Associated Disorders ... may include: • Cold ... hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... lymphoproliferative disorders ... microglobulin Treatment ... workup #oncology #hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Pathophysiology ... brain and spinal cord ... other neurological disorders ... limb or joint disorders ... #neurology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... Episcleritis Signs ... , breast CA - Hematologic ... Treatment: - Systemic ... #diagnosis #dermatology