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oncology causes chronic cll hemolytic leukemia lymphocytic management thrombocytosis agglutinin cancer cold dermatologic eosinophil eosinophilia erythematosus gap globulin gpa granulomatosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... • Rheumatic disorders ... • Celiac disease ... #Diagnosis #Algorithm ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... IBD, Celiac disease ... #Diagnosis #Algorithm ... #hematology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... Diagnosis Algorithm ... insufficiency • Vasculitis ... #skinrash #dermatology ... Diagnosis #Algorithm
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
to Anemia - Differential ... Diagnosis Algorithm ... #Approach #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... - Hemolytic anemia ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... cardiac valve, vasculitis ... Consider RBC membrane disorder ... Diagnosis #Algorithm ... #workup #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... glucocorticoid treatment ... symptoms (eg, skin ... #Algorithm #Differential ... #diagnosis #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Diagnosis: Vasculitis ... syndrome • Giant cell ... Polyangiitis #GPA #dermatology ... #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Viral Infection Clinical ... anemia • Cold ... younger pts) Differential ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... can indicate disease ... • Neutropenia, anemia ... #workup #oncology ... #hematology
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