616 results
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... pattern of spread, B symptoms ... ~10% - B-Cell ... Classification #pathophysiology ... #differential #algorithm
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Differential Diagnosis Algorithm ... - Increased Cell ... imports K+ into cells ... Differential #Diagnosis #Algorithm ... potassium #low #pathophysiology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in one cell ... mutated in all cells ... Retinoblastoma Signs / Symptoms ... Retinoblastoma #pathophysiology ... diagnosis #signs #symptoms
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Features of a Sickle Cell ... Crisis Sickle-cell ... These cells can ... The underlying pathophysiology ... Features #Signs #Symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... lineage ALL Symptoms ... thrombocytosis) CML Symptoms ... Symptoms: • Lymphadenopathy
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... with no early symptoms ... smear: Smudge cells ... or basket cells ... and other C Cell
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... Involvement - B-cell ... CD10 - T-cell ... - B-cell ... Differential #Diagnosis #Algorithm
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... promote dendritic cell ... These T cells then ... induce B-cell class ... #asthma #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
B and CD-4+ T cells ... CRP Neuronal cell ... surface targeted -> Cell ... RheumaticFever #pathophysiology ... diagnosis #signs #symptoms
Gastric Acid Secretion - Pathophysiology
Chief cell - Pepsinogen
Parietal cell - Acid, Intrinsic factor
G cell - Gastrin
Inhibitors:
Acid Secretion - Pathophysiology ... Chief cell - Pepsinogen ... Parietal cell - ... Intrinsic factor G cell ... Acid #Secretion #Pathophysiology