515 results
Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
Differential diagnosis ... of Langerhans cell ... : 'signet ring sign ... central dot. - LIP #Clinical ... Comparison #Table #RadiologyAssistant
On the left a chest film of a 19 year old patient with Langerhans cell histiocytosis.
The
with Langerhans cell ... challenging differential diagnosis ... the central dot sign ... #Clinical #Radiology ... Histiocytosis #Cystic #RadiologyAssistant
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... mutated in one cell ... Retinoblastoma Signs ... ophthalmology #diagnosis ... #signs #symptoms
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Pathogenesis and Clinical ... B and CD-4+ T cells ... CRP Neuronal cell ... pathophysiology #diagnosis ... #signs #symptoms
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... 40% of patients diagnosed ... Signs of immunodeficiency ... involved in B cell ... humoral immunity Signs
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma Diagnosis ... Management Summary Clinical ... Signs: • hyperCalcemia ... marrow plasma cells ... plasma clonal cell
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... yrs old; F>M Signs ... Anemia - Giant cells ... Pathophysiology #Diagnosis ... #Signs #Symptoms
On the left three different patients with lung cysts.
From left to right: Lymphangiomyomatosis, LIP and Langerhans
and Langerhans cell ... #Clinical #Diagnosis ... Histiocytosis #RadiologyAssistant
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... Orange or Hep C Clinical ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... Lymphocytic #Leukemia #diagnosis
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
& inflammatory cells ... ) Clinical: ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs