463 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... mutated in one cell ... Retinoblastoma Signs / Symptoms ... ophthalmology #diagnosis ... #signs #symptoms
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... - B symptoms ... Noncontiguous spread • Clinical ... Differential Diagnosis ... comparison #oncology #diagnosis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Pathogenesis and Clinical ... B and CD-4+ T cells ... CRP Neuronal cell ... pathophysiology #diagnosis ... #signs #symptoms
On the left three different patients with lung cysts.
From left to right: Lymphangiomyomatosis, LIP and Langerhans
and Langerhans cell ... #Clinical #Diagnosis ... Histiocytosis #RadiologyAssistant
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Reed-Sternberg (RS) Cells ... pattern of spread, B symptoms ... ~10% - B-Cell ... pathophysiology #Hematology #Diagnosis
Investigating DVT: approach to symptoms suggestive of lower limb deep vein thrombosis
#Diagnosis #DVT #deepvein #thrombosis #wells
DVT: approach to symptoms ... vein thrombosis #Diagnosis ... deepvein #thrombosis #wells ... assessment #evaluation #symptoms
Anaplastic large cell lymphoma, ALK+
Clinical
 • First 3 decades of life, M>F
 • Often nodal +
Anaplastic large cell ... lymphoma, ALK+ Clinical ... subtle • Small cell ... advanced stage + B symptoms ... ) • Donut cells
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... Orange or Hep C Clinical ... with no early symptoms ... phenomenon CLL Diagnosis ... Lymphocytic #Leukemia #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... lineage ALL Symptoms ... thrombocytosis) CML Symptoms ... Hematology #Oncology #Diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... old; F>M Signs/Symptoms ... Anemia - Giant cells ... Pathophysiology #Diagnosis ... #Signs #Symptoms