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diagnosis management hemophagocytic hlh lymphohistiocytosis treatment apml causes coagulation dic differentiation disseminated erectile hemeonc intravascular oncology rheumatology summary syndrome urology
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... and rigidity Endocrinologic ... Erectile Dysfunction ... -> Endothelia cell ... #Pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... , Hb), Hepatic dysfunction ... lymphoma, B-cell ... treatment #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... 64%) • Renal dysfunction ... • Respiratory dysfunction ... Schistocytes, helmet cells ... treatment #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Release from blast cells ... • Induce blast cell ... severe APLS, organ dysfuxtion ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... Persistent fever, organ dysfunction ... Pathophysiology ... and CD8+ T cells ... Diagnosis #Management #Hematology
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