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diagnosis treatment rheumatology oncology dermatology differential infection infectiousdiseases 1 acne adultonset aids anemia aplastic arteritis arthritis atopic atopy causes cdi
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Care TRICC - NEJM ... - ICU FOCUS - NEJM ... ALI is the deadliest ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Infectious ... Chest CT: • Ground-glass ... and M panel Management ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... +++: Virus (EBV, ... biologics (CMV +++, EBV ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... • Cytopenia -> BM ... pain, bleeding, infections ... bruising, bleeding, infection ... #Leukemia #Hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Renal: (AKI ... Other tests: • CT ... confirm DAH, r/o infection ... seen on chest CT ... differential #diagnosis #management
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Diaqnoses: • Infectious ... Coxsackie, CMV, EBV ... Disease #diagnosis #management ... #treatment #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in ... Opportunistic Infections ... enhancement on CT ... • Symptoms: AMS ... effect/Edema • EBV
Congenital Cytomegalovirus Infection- Ultrasonographic images showed ventricular dilatation in the fetal brain, and T2-weighted magnetic resonance
Cytomegalovirus Infection ... congenital CMV infection ... growth restriction, hematologic ... #clinical #NEJM ... radiology #MRI #CT
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... Neutropenia - recurrent infections ... Idiopathic • Infections ... Anemia #oncology #hematology ... #diagnosis #management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Clostridioides Difficile Infection ... Diagnosis and Management ... Acute Diarrhea (>3 BM ... #1 nosocomial infection ... equivocal • CT
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