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differential nephrology rheumatology acute aki algorithm hypertension injury kidney pulmonary secondary vasculitis anca antibodies antibody antineutrophil antinuclear classification diseases emergencies
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Diagnosis Baseline ... osmolarity If cause ... , ANA, Anti-GBM, ... biopsy • Abdominal
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP ... resolution chest CT ... #diagnosis #nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
vasculitis (AAV ... mononeuritis multiplex WORKUP ... Other tests: • CT ... Goodpasture's cause ... seen on chest CT
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Artery Stenosis, Abdominal ... Compartment Syndrome ... Emboli, Thrombosis, Vasculitis ... • GN: ANCA, Anti-GBM ... #nephrology #causes
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
- Differential Diagnosis ... ultrasound; MRA; abdominal ... • Cushing’s syndrome ... #Differential #Diagnosis ... #Workup #table
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
renal abnormalities ... often causes arthritis ... < 30 years - Aorta ... • GCA: - Aorta ... LFT • ESR • ANA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... • Sjögren syndrome ... 90% • Anti-GBM ... Jcortesizaguirr #ANA ... Antineutrophil #antibodies #diagnosis
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... Diagnosis Approach ... Coarctation of aorta ... , Vasculitis • ... #Hypertension #Workup
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
renal abnormalities ... < 30 years • Aorta ... Arteritis): • Aorta ... often causes arthritis ... pain and GN Anti-GBM
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
suspected) - CT ... if abdominal pain ... Treat underlying cause ... , hypotension, renal ... Oncology #HemeOnc #Diagnosis
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