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differential nephrology rheumatology acute aki algorithm injury kidney pulmonary vasculitis ana antibodies antibody antineutrophil antinuclear classification diseases emergencies hemeonc management
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP ... resolution chest CT ... #diagnosis #nephrology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... • Sjögren syndrome ... 90% • Anti-GBM ... Jcortesizaguirr #ANA ... Antineutrophil #antibodies #diagnosis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... and Differential Diagnosis ... osmolarity If cause ... , ANA, Anti-GBM, ... biopsy • Abdominal
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... tract, and often causes ... < 30 years - Aorta ... LFT • ESR • ANA ... • Urinalysis (Renal
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Artery Stenosis, Abdominal ... Compartment Syndrome ... Emboli, Thrombosis, Vasculitis ... • GN: ANCA, Anti-GBM ... #nephrology #causes
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... vasculitis (AAV ... mononeuritis multiplex WORKUP ... Other tests: • CT ... seen on chest CT
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... < 30 years • Aorta ... Arteritis): • Aorta ... tract, and often causes ... gut involvement, abdominal
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
suspected) - CT ... if abdominal pain ... Treat underlying cause ... , hypotension, renal ... Oncology #HemeOnc #Diagnosis
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